CYP21A2 is an important enzyme that controls steroid hormone levels. It produces the hormones cortisol and aldosterone, while it decreases testosterone levels. Mutations that decrease the activity of the enzyme are fairly common, and many people are carriers. They are associated with more masculine physical traits in women and lower fertility in both sexes. However, these people also have a lower risk of developing mood and stress-related disorders. Read on to find out more about this enzyme and its variants.
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